Serotonin Receptor 5-HT2B Mediates Serotonin-Induced Mechanical Hyperalgesia
نویسندگان
چکیده
منابع مشابه
Serotonin receptor 5-HT2B mediates serotonin-induced mechanical hyperalgesia.
Serotonin [5-hydroxytryptamine (5-HT)] released from mast cells or platelets in peripheral tissues is one of the important inflammatory mediators in pain and hyperalgesia. The involvement of 5-HT in pain is complex because it could inhibit or facilitate nociceptive transmission, reflecting the presence of multiple 5-HT subtype receptors on peripheral and central nociceptors. The present study a...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2011
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.4682-10.2011